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Pathophysiology of Diabetic Foot: Questions and Answers

What is the definition of Diabetic Foot?

Diabetic foot is a disease complex that can develop in the skin, muscles and bones of the feet as a result of the nerve damage, poor circulation and/or infection that is associated with diabetes.

Diabetic Foot Spectrum
Diabetic Foot Spectrum
What proportion of diabetics will develop diabetic foot ulcers during their lifetime?
15% of  all diabetic individuals during their life time

What is the most common cause of lower limb amputations?
85% of amputations are preceded by diabetic foot ulcers

In India, what is the most common type of diabetic foot presentation, Neuroischemic or Neuropathic?
In west most common indication for major limb amputation is neuro-ischemic foot while in India it is neuropathic foot with secondary infection mainly because of suboptimal or delayed treatment of diabetes

What are various classification and grading systems for Diabetic foot ulcers?

  • Wagner 's Diabetic Foot Grading System
  • University of Texas Wound Classification System
  • PEDIS Ulcer classification system

Read More: http://www.worldsurgeryforum.net/2016/06/classification-and-grading-systems-for.html

What are various pathophysiological factors which contribute to causing Diabetic foot syndrome?

  • Diabetic Macroangiopathy
  • Diabetic Microangiopathy
  • Diabetic Polyneuropathy
  • Diabetic Osteoarthropathy
  • Reduced resistance to infection
  • Delayed wound healing
  • Reduced rate of collateral vessel formation
How does Diabetic Polyneuropathy contribute to the causing of diabetic foot?

Diabetic Polyneuropathy leading to ulcer formation
Diabetic Polyneuropathy leading to ulcer formation

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