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TUMOR BIOLOGY AND TUMOR MARKERS IMPORTANT MCQ POINTS PPT



  • Induction of apoptosis is either death receptor
    dependent (extrinsic pathway) or independent (intrinsic pathway) 


  • The two best understood death receptor pathways are the Fas receptor and death receptor 5 that bind the extracellular Fas ligand and TRAIL, respectively. (MCQ)


  • Cytochrome c is directly involved in the activation of caspase 9, which activates caspase 3, which then leads to apoptosis (MCQ) 


  • Angiogenesis inhibitors are associated with specific tissues or circulate in the blood. These are interferon-α, thrombospondin, tumstatin, canstatin, endostatin, and angiostatin. (MCQ) 


  • Most telling are the results of clinical studies with the anti-VEGF antibody bevacizumab (Avastin), the first angiogenesis inhibitor approved by the Food and Drug Administration for treatment of colon cancer. Bevacizumab significantly prolongs the survival of patients with advanced cancer. (MCQ)


  • Please continue reading in the presentation embedded below...




Reference


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